Review article that looks at the present and future of treatment paradigms for sarcomatoid renal cell carcinoma. From: Candelario, et al., Kidney Cancer, Vol.5, Iss.5, pp. 167-179, 2021

Review article that looks to validate the association of rs307826 in VEGFR3 to first-line sunitinib outcome in an independent cohort of m-ccRCC patients. From: Beuselinck, et al., Kidney Cancer, Vol.4, Iss.3, pp. 139-149, 2020

Renal cell carcinoma with inferior vena cava extension. A modified thrombus classification was proposed with visuals of successive levels defined, in part, as shown in the visual. From: Leibovich, et al., Kidney Cancer, Vol.4, Iss.2, pp. 111-115, 2020

This research article examines the role microRNAs (miRNAS) in the progression of cancer types, including clear cell renal cell carcinoma (ccRCC). L: Prognostic miRNAs (pink) and master regulator (blue) of the prognostic genes. R: Identified 96 miR-22 target genes. From: Gong, et al., KCA 3:2, pp. 119-132, 2019

This review examines cell-free circulating tumor DNA (ctDNA) in metastatic renal cell carcinoma. Visual illustrates circulating cell-free DNA (cfDNA) and ctDNA found in serum and plasma fractions from blood. From: Hahn, et al., Kidney Cancer, Vol.3, Iss.1, pp. 7-13, 2019

This review examines radiation therapy in the treatment of renal cell carcinoma with an aim to expand the discussion on treatment options. Visual is an example of a patient treated with stereotactic ablative radiotherapy for a renal tumor. From: Choi and Yu, Kidney Cancer, Vol.3, Iss.1, pp. 1-6, 2019

This study indicates that 4LT appears to have activity in mRCC patients. The figure shows total number of patients receiving the therapies (A); with (B) indicating therapies given to patients who received 4LT. From: Stukalin, et al., Kidney Cancer, Vol.2, Iss.1, pp. 31–36, 2018.

Renal cell carcinoma's disease biology: inactivated VHL gene leads to overexpression of HIF. Genes activated by HIF transcript growth factors such as VEGF, PDGF and FGF. From: Maia et al., Kidney Cancer, Vol.1, Iss.1, pp. 15-29, 2017

Rationale to prime the immune system with PD-1 blockade prior to nephrectomy. From: Harshman et al., Kidney Cancer, Vol.1, Iss.1, pp. 31-40, 2017

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