Submission Guidelines





Authors are requested to submit their manuscript electronically to the online submission system msTracker.

Note that the manuscript should be uploaded as one file with tables and figures included. This file can be a Word document, a PDF, or an embedded or zip file (.rar) if separate high resolution figures or a supplemental file such as a video are also to be included with the submission (the file size maximum for a video is 25MB). If the video is too large to submit, please contact to arrange a file transfer. For further information, see “Supplementary Data” below.

Resubmissions should include the manuscript number in the cover letter. Resubmissions should clearly mention that the submission is a revision and include the reference number in the submission letter. The author's replies to the reviewer comments should be included in the revised manuscript itself (at the top). The revised paper should always be a Word document. Manuscripts not revised within 6 months of first submission will generally be considered as new submissions and re-refereed accordingly.

Submission of an article is understood to imply that the article is original and unpublished and is not being considered for publication elsewhere. Kidney Cancer is committed to the highest ethical standards and best practices in publishing and follows the code of conduct for Committee On Publication Ethics/DOAI and the ICMJE. Any possible conflict of interest, financial or otherwise, related to the submitted work must be clearly indicated in the manuscript. Procedures involving experiments on human subjects should be in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975. Procedures involving experimentation on animal subjects should be in accord with either the guide of the institution in which the experiments were done, or with the National Research Council’s guide for the care and use of laboratory animals.

If the address to which proofs should be sent is different from the correspondence address, authors are kindly requested to indicate this. Both the editor and the publisher should be informed of any changes in either or both of these addresses. Please also supply a direct telephone number and a fax number, if available.


Research Reports

Organization and style of presentation

Manuscripts must be written in US English. Authors whose native language is not English are recommended to seek the advice of a native English speaker or English language service before submitting their manuscripts. A language or editing service that we recommend is PeerWith.

Manuscripts should be double spaced throughout with wide margins (2.5cm or 1in), including the abstract and references. Every page of the manuscript, including the title page, references, tables, etc., should include a page number centered at the bottom.

Manuscripts should be organized in the following order with headings and subheadings typed on a separate line, without indentation.

Title Page

  1. Title (should be clear, descriptive and concise).
  2. Full name(s) of author(s) and higher degrees.
  3. All authors should meet the following 4 criteria: (a) have made substantial contributions to the work, (conception, performance or interpretation of data); (b) writing the article; (c) approve the final version to be published; (d) agreed to be accountable for the accuracy and integrity of the work.
  4. Full affiliation(s). Delineate affiliations with lowercase letters.
  5. Present address of author(s), if different from affiliation.
  6. Running title (45 characters or less, including spaces).
  7. Complete correspondence address, including telephone number, fax number and e-mail address.

Leave the author information blank if double-blind peer review is wished for, but do include the information in the submission letter to the editor.

Abstract and Keywords

The abstract for research papers should follow the “structured abstract” format:






The abstract should try to be no longer than 250 words.

For other papers such as Reviews, the abstract should be clear, descriptive, and self-explanatory, and no longer than 250 words.

Include a list of 4-10 keywords. These keywords should be terms from the MeSH database.

The abstract should make clear the context and aims for the study. It should also state how it was conducted, the main findings and conclusions drawn. Clinical trial abstracts should include items deemed essential by the CONSORT group.


This should outline the context for and purpose of the study.

Materials and Methods

There is no word limit to the materials and methods section, as the journal’s policy is that methodological rigour and reproducibility is of great importance. This section should aim to be sufficiently detailed to enable others with access to the data to reproduce the results.

Cell line identity

  1. In keeping with scientific consensus guidelines, the Journal considers it to be good practice for cultured cell lines to be authenticated. For each cell line, authors should include in the Methods section a statement that specifies:
  2. Source of the cell lines
  3. Are any cell lines used in this paper listed in the database of commonly misidentified cell lines maintained by the International Cell Line Authentication Committee (ICLAC)? If yes, include in the Methods section a scientific justification of their use
  4. If the cell lines been authenticated and by which method
  5. If the cell lines been tested for mycoplasma contamination and if so, date last tested

Microarray Data

The Journal has adopted the microarray data standard developed by the Microarray Gene Expression Data Society (MGED), requiring that all authors using microarray data analysis in their research submit a complete data set to the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus database (GEO; prior to manuscript submission. Papers submitted to the Journal that use microarray data analysis must comply with the “minimum information about microarray experiments” (MIAME) standard. Access to the GEO database is free and open for all, and the database is maintained by NCBI (Cheadle C, Cho-Chung YS, Becker KG, and Vawter MP. Application of z-score transformation to Affymetrix data. Appl Bioinformatics. 2003; 2(4): 209-217.)


These should be presented in a logical order and summarize the salient findings.


This should link the conclusions with the aims of the study but avoid overinterpreting the study’s findings.

Acknowledgments including sources of support

Conflict of Interest

If there is no conflict of interest to declare, do still include this section and insert “The authors have no conflict of interest to report”.


  • Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in a list of references following the text of the manuscript. Only articles published or accepted for publication should be listed in the reference list. Submitted articles can be listed in the text as (Author(s), unpublished data).
  • All authors should be listed in the reference list.
  • References should be listed in the order of appearance in Vancouver style:

[1] Grossman HB, Natale RB, Tangen CM, Speights VO, Vogelzang NJ, Trump DL, et al. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med. 2003;349(9):859-66.

[2] Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA. Medical microbiology. 4th ed. St. Louis: Mosby; 2002.

[3] Berkow R, Fletcher AJ, editors. The Merck manual of diagnosis and therapy. 16th ed. Rahway (NJ): Merck Research Laboratories; 1992.

[4] Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGrawHill; 2002. p. 93113.

[5] Canadian Cancer Society [homepage on the Internet]. Toronto: The Society; 2006 [updated 2006 May 12; cited 2006 Oct 17]. Available from:


Number according to their sequence in the text. The text should include references to all tables.

Provide each table on a separate page of the manuscript after the references.

Include a brief and self-explanatory title with any explanations essential to the understanding of the table given in footnotes at the bottom of the table.

Vertical lines should not be used to separate columns. Leave some extra space between the columns instead.

Figure Legends

The author is required to have obtained patient permission from all recognizable participants in photographs, videos, or other information that may be published in the Journal or on the journal’s website. A statement that permission was granted by the patient must accompany the figure legend. Do not use study participants' names, initials, or hospital numbers in the legend, figure, or anywhere in the manuscript.


Number the figures according to their sequence in the text. The text should include references to all figures.

For the file formats of the figures please take the following into account:

  • Line art should have a minimum resolution of 1200 dpi, save as EPS or TIFF.
  • Do not use faint lines and/or lettering and check that all lines and lettering within the figures are legible at final size.
  • All lines should be at least 0.1 mm (0.3 pt) wide.
  • Vector graphics containing fonts must have the fonts embedded in the files.
  • Grayscales (incl photos) should have a minimum resolution of 300 dpi, or 600 dpi for combination art (lettering and images); save as TIFF.
  • Do not save figures as JPEG, this format may lose information in the process
  • Do not use figures taken from the Internet, the resolution will be too low for printing
  • Do not use color in your figures if they are to be printed in black & white, as this will reduce the print quality (note that in software often the default is color, you should change the settings)
  • For figures that should be printed in color, please send a CMYK encoded EPS or TIFF

Figures should be designed with the format of KCA in mind and preferable sized as they will appear when printed. A single column of the journal is 77mm and two columns are 165mm.

Figures should be cropped to include the figure only (no blank space).

On figures where a scale is needed, use bar scales to avoid problems if the figure needs to be reduced.

Each illustration should have a brief self-explanatory legend that should be typed separately from the figure in the section of the manuscript following the tables.

Costs for color figures in the print version of the journal are as follows: 1 figure - 650 euro; 2 figures - 900 euro; 3 figures - 1050 euro; 4 figures - 1200 euro; 5 figures - 1350 euro. Cost for each additional color figure will be 150 euro. Color figures are free in the electronic version of the journal. You may opt to send in both black/white figures for print, and color figures for the online PDF (please adjust the figure legend appropriately).

Supplementary Data

Supplementary data can be submitted with the manuscript, included within the manuscript after the Figures and Tables (or otherwise after the References). Each supplementary item should have a legend and should not exceed the file size of 10MB. Supplemental videos can be submitted separately (see top of page for submission guidelines of videos). A short description of the supplementary items should be included under the header of “Supplementary Material” within the manuscript before the “References”. Large datasets should be hosted on the author’s own or institute’s website or in an appropriate database, and should be properly cited within the manuscript.


Reviews should be authoritative and topical and provide comprehensive and balanced coverage of a timely and/or controversial issue.Reviews should be prepared as detailed above for a Research Report omitting Introduction through Discussion, and include a Conclusion. When submitting a Review, clearly signify the article as such in the submission title by using: "REVIEW: full article title".

Short Communications

A short communication is an article of original scholarship of unusual interest of less than 1500 words (not including references). An abstract of 100 words or less should be included with no subdivision of text into sections. References should be formatted as above. A total of two tables and/or figures are allowed.


A hypothesis article should be a balanced and insightful consideration of a topic with novel hypotheses well presented and supported. The article should be prepared as a Research Report but without Methods or Results sections.

Book Reviews

Book reviews should be 750 words or less and without sections. Suggestions can be proposed to the Editors-in-Chief.

Letters to the Editor

Authors can submit comments of 1000 words or less concerning prior articles published in KCA to the Editors-in-Chief through the Editorial Office (


Commentaries can be around 1000 words with an abstract and no other subdivisions.


In cover letter

Name, postal address, phone number, fax number and e-mail address of the corresponding author.

Name of an Associate Editor with expertise in the area of the study (if no Associate Editor is suitable, the Editorial Office will handle the submission).

Statement that all authors have contributed to the work, agree with the presented findings, and that the work has not been published before nor is being considered for publication in another journal.

A list of at least 4-6 potential reviewers knowledgeable in the area of the study and potential reviewer conflicts.

Statement that procedures involving experiments on human subjects are done in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975.

Statement that procedures involving experimentation on animal subjects are done in accord with either the guide of the institution in which the experiments were done, or with the National Research Council's guide for the care and use of laboratory animals.

All affiliations with or financial involvement (e.g., employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, royalties) with any organization or entity, independent of relevance to the particular manuscript, are completely disclosed in the letter of submission.

In manuscript

Where applicable, a statement of compliance with guidelines, and inclusion of a flow chart, for respectively

randomized trials: CONSORT (;

observational studies: STROBE (;

studies of diagnostic accuracy: STARD (;

systematic reviews and meta-analyses: PRISMA (

Compliance with guidelines on human experimentation as well as protocol approval by a local Institutional Review Board should be specified.

Compliance with guidelines of animal experimentation as well as protocol approval by the Institutional Animal Care and Use Committee should be specified.

Statement of all financial and material support, independent of relevance to the particular manuscript, and any potential conflicts should also be clearly identified in the Acknowledgment and Conflict of Interest sections. If there is no Conflict-of-Interest then still add this statement.

All financial and material support are clearly identified in the manuscript, including listing of support specified in the letter of submission.


Resubmissions should include the manuscript number and a reference that the paper is a revision. The point-by-point response to the previous reviews should be included at the top of the manuscript.


Authors of published articles (non-prepress, final articles) will be contacted by Kudos. Kudos is a service that helps researchers maximize the impact and visibility of their research. It allows authors to enrich their articles with lay metadata, add links to related materials and promote their articles through the Kudos system to a wider public. Authors will receive no more than three emails: one invitation and a maximum of two reminders to register for the service and link the published article to their profile. Using and registering for Kudos remains entirely optional. For more information, please have a look at our authors section.